Reduction of age-related chronic inflammation with photobiomodulation
With age, chronic inflammation becomes an underlying factor in many aging-related conditions, affecting not only quality of life but also lifespan. This phenomenon, often referred to as “inflammaging,” is characterized by persistent, low-grade inflammatory activity in the body. Photobiomodulation is emerging as an innovative solution to regulate these inflammatory processes, offering a non-invasive and effective approach to promote overall well-being.
Biological causes of chronic inflammation with age
Chronic inflammation results from a disturbed balance between inflammatory and anti-inflammatory responses in the body. With age, this imbalance can be compounded by factors such as oxidative stress, the accumulation of senescent cells (aging cells that no longer divide), and impaired immune function. These disturbances lead to a continued release of pro-inflammatory cytokines, molecules that contribute to progressive cellular and tissue damage.
How photobiomodulation works against chronic inflammation
Photobiomodulation, using specific wavelengths in the red and near-infrared spectra, penetrates deep into tissues to modulate biological processes. By stimulating mitochondria, it promotes an increase in ATP production, thereby reducing excessive inflammatory signals. It also acts on cell signaling pathways to:
- Regulate cytokine production: Photobiomodulation decreases the release of pro-inflammatory cytokines while increasing those with anti-inflammatory properties, restoring a healthy balance.
- Improve lymphatic drainage: This light stimulation facilitates the elimination of cellular waste and toxins, reducing local inflammation.
- Protect tissues from damage: By increasing intracellular antioxidant levels, it minimizes the effects of free radicals responsible for chronic inflammation.
Photobiomodulation and reduction of inflammation in neuroinflammatory disorders
A growing field of exploration concerns the use of photobiomodulation to reduce inflammation in neuroinflammatory disorders. These disorders, such as Alzheimer’s disease or multiple sclerosis, are characterized by chronic inflammation of the central nervous system. Photobiomodulation, by targeting neurons and glial cells, helps to decrease the levels of specific inflammatory cytokines, thereby reducing the progression of neuronal damage.
Preliminary studies show that the application of red and infrared light to the skull can stimulate neuronal regeneration while decreasing inflammatory markers. This offers a promising perspective to improve the quality of life of people with neurodegenerative disorders by slowing their progression.
Integrating photobiomodulation into a preventive approach
To maximize the benefits of photobiomodulation, it is essential to integrate it into a comprehensive preventive strategy. For example, regular sessions can be supplemented with a diet rich in anti-inflammatory foods, such as red fruits, nuts, and oily fish. Similarly, moderate physical activity can enhance the anti-inflammatory effects of this technology.
Reducing chronic age-related inflammation with photobiomodulation represents a unique opportunity to promote sustainable health and a better quality of life. By acting directly on the biological processes responsible for inflammation, this technology offers a natural and effective approach to preserving long-term well-being. Integrated into a comprehensive health strategy, photobiomodulation opens new perspectives for harmonious and active aging.